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Outcome After Spinal Reirradiation for Malignant Epidural Spinal Cord Compression
Ann Neurol 37:585-589, Schiff,D.,et al, 1995
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Article Abstract
All patients were ambulatory following the first course of radiation,40 (74%)were ambulatory at the onset of reirradiation,and 42(78%)were ambulatory at the end of reirradiation.Thirty-seven patients(69%)remained ambulatory at their last follow-up 6 days to 80 months following reirradiation(median,4.7 months.Five patients eventually became nonambulatory 6.5 to 35 months following reirradiation.Median survival for all patients following reirradiation was 4.2 months.We conclude that for cancer patients with progressive epidural disease following radiotherapy, reirradiation frequently preserves ambulation and carries minimal risk of radiation myelopathy during the patients'lifetime.
 
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myelopathy,radiation induced
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radiation therapy,CNS treatment and complications with
spinal cord,compression of
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spine,metastasis to
treatment of neurologic disorder

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